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Renling Pei, Ye Xu, Yan Wei, Tao Ouyang, Jinfeng Li, Tianfeng Wang, Zhaoqing Fan, Tie Fan, Benyao Lin, Yuntao Xie
Frontiers of Medicine 2013, Volume 7, Issue 1, Pages 138-142 doi: 10.1007/s11684-013-0247-5
Keywords: SIPA1 polymorphism metastatic breast cancer survival
Ripen NSENGA MD, Longxian CHENG PhD, Mei’an HE PhD, Tangchun WU PhD,
Frontiers of Medicine 2009, Volume 3, Issue 4, Pages 437-442 doi: 10.1007/s11684-009-0074-x
Keywords: natriuretic peptide precursor A coronary heart disease gene polymorphism allelic discrimination polymorphism
Polymorphism of pharmaceutical molecules: perspectives on nucleation
Jie LU, Zhen LI, Xiaolin JIANG,
Frontiers of Chemical Science and Engineering 2010, Volume 4, Issue 1, Pages 37-44 doi: 10.1007/s11705-009-0294-2
Keywords: development Polymorphism elucidation controversial relationship
Genetic association between the polymorphism of cytosolic PLA2 gene family and schizophrenia
Qiong YU PhD, Xiang-Fei MENG PhD, Jie-Ping SHI, Ya-Qin YU PhD,
Frontiers of Medicine 2010, Volume 4, Issue 1, Pages 101-105 doi: 10.1007/s11684-010-0017-6
Keywords: schizophrenia cytosolic phospholipase A2 ligase detection reaction polymorphism
Polymorphism and crystal transformation of penicillin sulfoxide
Dingding JING, Yongli WANG, Zhijian CHEN, Lina ZHOU, Jingkang WANG
Frontiers of Chemical Science and Engineering 2011, Volume 5, Issue 4, Pages 442-447 doi: 10.1007/s11705-011-1140-x
Keywords: penicillin sulfoxide crystallization polymorphism crystal transformation Raman spectroscopy
TANG Zhongzhi, LI Junyao, YANG Jianhong
Frontiers of Medicine 2008, Volume 2, Issue 2, Pages 178-181 doi: 10.1007/s11684-008-0033-y
Association study on GNB3 gene polymorphism with essential hypertension in Xinjiang Uygur group
JING Jianying, WANG Dan, WANG Xiaofeng, JIN Jianzhong, JIN Li, JIAO Yi, WEN Hao, LIN Renyong
Frontiers of Medicine 2007, Volume 1, Issue 2, Pages 230-233 doi: 10.1007/s11684-007-0045-z
Keywords: case-control significant difference reaction-restriction fragment C825T polymorphism evidence
SUN Pin, ZHANG Zhongbin, WU Fen, WAN Junxiang, JIN Xibeng, XIA Zhaolin
Frontiers of Medicine 2007, Volume 1, Issue 3, Pages 320-326 doi: 10.1007/s11684-007-0062-y
Keywords: case-control rs2854451 regression analysis haplotype further research
ZHAO Yangguo, WANG Aijie, REN Nanqi, ZHAO Yan
Frontiers of Environmental Science & Engineering 2008, Volume 2, Issue 1, Pages 116-121 doi: 10.1007/s11783-008-0018-8
Keywords: technique single-strand proportion bioreactor community diversity fingerprinting technique
Du Yan, Han Xue, Pu Rui, Xie Jiaxin, Zhang Yuwei, Cao Guangwen
Frontiers of Medicine 2014, Volume 8, Issue 2, Pages 217-226 doi: 10.1007/s11684-014-0326-2
This study was designed to investigate the contribution of miRNA-122-binding site polymorphism at
Keywords: hepatocellular carcinoma (HCC) interaction miRNA-122-binding site IL-1A rs3783553 hepatitis B virus (HBV) mutations
Osteopontin is a promoter for hepatocellular carcinoma metastasis: a summary of 10 years of studies
Lunxiu Qin
Frontiers of Medicine 2014, Volume 8, Issue 1, Pages 24-32 doi: 10.1007/s11684-014-0312-8
In this review, we summarize the novel findings from our series of studies on the leading metastasis-related gene, osteopontin (OPN). In our previous gene expression profiling study, OPN was identified as one of the leading genes associated with the metastasis of hepatocellular carcinoma (HCC). We focused on OPN to evaluate its prognostic values and important roles in HCC metastasis. A retrospective study of large cohorts of HCC patients demonstrated that plasma OPN level was one of the leading independent prognostic factors for HCC patients, even in the early stage of HCC, and could serve as a surrogate serologic biomarker for monitoring the treatment response and tumor recurrence after HCC resection. Using both in vitro and in vivoinvestigations, we found that OPN has an important role in metastasis and tumor growth of HCC and is an attractive potential therapeutic target for combating HCC metastasis. We also found that OPN+ HCC cells have much more amplifications at chromosomal regions, and promoter polymorphisms are important in the regulation of OPN expression and tumor growth and lung metastasis of HCC.
Keywords: osteopontin (OPN) hepatocellular carcinoma metastasis prognosis therapeutic target biomarker genetic polymorphism
Current molecular biologic techniques for characterizing environmental microbial community
Dawen GAO, Yu TAO
Frontiers of Environmental Science & Engineering 2012, Volume 6, Issue 1, Pages 82-97 doi: 10.1007/s11783-011-0306-6
Keywords: microbial community denaturing gradient gel electrophoresis (DGGE) terminal restriction fragment length polymorphism
G-quadruplex formation of oligonucleotides containing ALS and FTD related GGGGCC repeat
Jasna Brčić,Janez Plavec
Frontiers of Chemical Science and Engineering 2016, Volume 10, Issue 2, Pages 222-237 doi: 10.1007/s11705-016-1556-4
Keywords: G-quadruplex GGGGCC NMR ALS/FTD polymorphism
Xunan YANG, Shan HUANG, Qunhe WU, Renduo ZHANG, Guangli LIU
Frontiers of Environmental Science & Engineering 2013, Volume 7, Issue 6, Pages 851-859 doi: 10.1007/s11783-013-0569-1
Keywords: heavy metals nutrients sediment profile terminal restriction fragment length polymorphism
Novel polymorphic EST-based microsatellite marker isolation and characterization from
Manosh Kumar BISWAS,Peng CHEN,Mohamed Hamdy AMAR,Xiuxin DENG
Frontiers of Agricultural Science and Engineering 2015, Volume 2, Issue 1, Pages 60-65 doi: 10.15302/J-FASE-2015048
Keywords: microsatellite polymorphism Poncirus trifoliata
Title Author Date Type Operation
Association of SIPA1 545 C>T polymorphism with survival in Chinese women with metastatic breast cancer
Renling Pei, Ye Xu, Yan Wei, Tao Ouyang, Jinfeng Li, Tianfeng Wang, Zhaoqing Fan, Tie Fan, Benyao Lin, Yuntao Xie
Journal Article
The role of natriuretic peptide precursor A gene polymorphism in the development of coronary heart disease
Ripen NSENGA MD, Longxian CHENG PhD, Mei’an HE PhD, Tangchun WU PhD,
Journal Article
Polymorphism of pharmaceutical molecules: perspectives on nucleation
Jie LU, Zhen LI, Xiaolin JIANG,
Journal Article
Genetic association between the polymorphism of cytosolic PLA2 gene family and schizophrenia
Qiong YU PhD, Xiang-Fei MENG PhD, Jie-Ping SHI, Ya-Qin YU PhD,
Journal Article
Polymorphism and crystal transformation of penicillin sulfoxide
Dingding JING, Yongli WANG, Zhijian CHEN, Lina ZHOU, Jingkang WANG
Journal Article
Relationship of endothelial nitric oxide synthase gene polymorphism with blood pressure, lipid profile
TANG Zhongzhi, LI Junyao, YANG Jianhong
Journal Article
Association study on GNB3 gene polymorphism with essential hypertension in Xinjiang Uygur group
JING Jianying, WANG Dan, WANG Xiaofeng, JIN Jianzhong, JIN Li, JIAO Yi, WEN Hao, LIN Renyong
Journal Article
Association of the genetic polymorphism of EPHX1 and EPHX2 with the susceptibility to chronic benzene
SUN Pin, ZHANG Zhongbin, WU Fen, WAN Junxiang, JIN Xibeng, XIA Zhaolin
Journal Article
community structure in different wastewater treatment processes characterized by single-strand conformation polymorphism
ZHAO Yangguo, WANG Aijie, REN Nanqi, ZHAO Yan
Journal Article
Association of miRNA-122-binding site polymorphism at the interleukin-1 α gene and its interaction with
Du Yan, Han Xue, Pu Rui, Xie Jiaxin, Zhang Yuwei, Cao Guangwen
Journal Article
Osteopontin is a promoter for hepatocellular carcinoma metastasis: a summary of 10 years of studies
Lunxiu Qin
Journal Article
Current molecular biologic techniques for characterizing environmental microbial community
Dawen GAO, Yu TAO
Journal Article
G-quadruplex formation of oligonucleotides containing ALS and FTD related GGGGCC repeat
Jasna Brčić,Janez Plavec
Journal Article
Diversity and vertical distributions of sediment bacteria in an urban river contaminated by nutrients and heavy metals
Xunan YANG, Shan HUANG, Qunhe WU, Renduo ZHANG, Guangli LIU
Journal Article